Standing up for the people we love:

You Made a Real Difference

For the 15th year in a row, we hit our $5 million donation goal for Stand Up To Cancer. Thanks to everyone who used their Mastercard at qualifying grocery stores and restaurants. Every purchase made an impact.*

Stand Up with the Jonas Brothers and Us

Mastercard and Stand Up To Cancer brought a group of people affected by cancer and their loved ones to New York to share their stories. What they didn’t know was that the Jonas Brothers would be there to honor each person and perform a song just for them.

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The Sound of Standing Up

“I Can’t Lose” by the Jonas Brothers is dedicated to everyone standing up to cancer. Play it loud. Share it wide. Because we can’t lose when we stand up together.

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The Ways You Can Continue To Stand Up To Cancer

Whether it’s big or small, every act of support matters. Here are some of the ways you can Stand Up To Cancer.

Share Your Story

How do you Stand Up To Cancer? Share your story using #StandUpWithMastercard and we’ll all honor the incredible ways we all stand up together.*

Stand with Us Again at the World Series

Tens of thousands of you stood up at the All-Star Game. Now we’re bringing that same energy to the World Series to honor those impacted by cancer.

Ignite Your Passions and Make an Impact

Explore priceless experiences that help support Stand Up To Cancer.

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We make real impact when we stand together

Since 2010, Mastercard has helped donate over $75 million to Stand Up To Cancer. Thank you for every way you've stood up. #StandUpWithMastercard

*We have reached our maximum donation amount of $5,000,000 for our 2025 Stand Up To Cancer campaign based on online orders and taps in store at qualifying restaurants and grocery stores. Stand Up To Cancer (SU2C) is a 501(c)(3) charitable organization. ©2025 Mastercard. All rights reserved.